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According to Morris water maze task, Gpx4 KO mice showed obvious defects in spatial learning and memory function, while ferroptosis inhibitor Lip-1 could ameliorate the neurodegeneration in these mice (Hambright et al., 2017)

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Les axes de recherche voqus proviennent majoritairement de modles animaux et cellulaires, restent strictement exprimentaux et ne constituent pas des indications thrapeutiques