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In cellular and mouse PD models, melatonin decreased the polarization of microglia to M1 and increased the anti-inflammatory M2 through upregulation of its ROR receptors that were downregulated with PD induction [389]

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Alternatives to Glutathione Supplements If youre hesitant about supplements, consider these alternatives to boost glutathione naturally: N-Acetylcysteine (NAC): A precursor to glutathione, NAC is clinically proven to raise levels and is safer for long-term use

While CoQ10 is an antioxidant and DFX is an iron chelator, both exert anti-ferroptotic effects