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doi: 10.1007/s00415-018-8800-4 146 MonsellS

This interaction is directly regulated by redox factor-1 and thioredoxin [109, 110]

Patients with PCOS presenting with hyperandrogenic manifestations such as hirsutism, acne and alopecia may benefit from anti-androgen therapies (e.g., spironolactone, flutamide, or finasteride) that inhibit androgen synthesis or receptor activity, thereby ameliorating cutaneous and pilosebaceous symptoms (Lizneva et al., 2016)