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doi: 10.1016/j.redox.2021.102215 31 MiaoYCuiZGaoQRuiRXiongB

Ferroptosis is an iron-dependent, lipid peroxidation-driven cell death pathway characterized by the accumulation of lipid reactive oxygen species (ROS) and disruptions in redox homeostasis, iron metabolism, and lipid regulation (Dixon and Olzmann, 2024)

Furthermore, another investigation revealed that Qi-Shen-Tang, a TCM formula containing Gouqizi and Danshen in a 1:1 ratio, can suppress ferroptotic characteristics of the retina in mice with RP by blocking the NFE2L2/GPX4 signaling pathway (Xiong et al., 2023)