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Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons

NTR1 agonists can exert neuroprotective effects and improve cognitive function by alleviating excessive microglial activation and inhibiting oxidative stress, cell apoptosis, and synaptic loss in the hippocampus [67, 68]

They play crucial roles in numerous biological processes, acting as messengers within the body to signal various functions such as tissue repair, immune response, and hormone regulation