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Using the biosensor-based gating strategy, we sorted BMDMs infected with Mtb -roGFP2 at 24 h post-infection (p.i.), treated them with anti-TB drugs (INH, RIF, moxifloxacin (MOXI), and bedaquiline (BDQ) at 3X the in vitro minimum inhibitory concentration [MIC]) for 48 h, and confirmed that the E MSH -reduced fraction is uniformly more tolerant to multiple anti-TB drugs than the E MSH -oxidized fraction (Suppl

This method is particularly effective for assessing molecules with a mass of less than 1500 Da, including nucleotides, carbohydrates, lipids, amino acids, and various other organic compounds [10, 11]

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(1998) Molecular Biology of the Cell