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The results indicate that focusing on the METTL3/HMGB1 pathway might provide a new therapeutic approach for treating KOA [113]

Introduction Amyotrophic Lateral Sclerosis (ALS) is a heterogeneous neurodegenerative disease that primarily affects both upper and lower motor neurons, leading to their progressive degeneration and subsequent, often rapid loss of motor function and death (Brotman et al., 2022)

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Before we dive into the why, let's take a look at what happened to Stephen when he started taking the wrong vitamins: One day, Stephen started taking a multivitamin containing Vitamin B12, biotin, iodine, and kelp , and sometimes he took it twice a day to be even healthier. His skin blew up