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While comprehending the precise etiological mechanisms of MetS remains challenging, evidence underscores the pivotal roles of aberrations in lipid metabolism and insulin resistance (IR) in its pathogenesis

The search strategy involved using the following keywords either individually or in combination: (Coenzyme Q10 OR Dehydroepiandrosterone OR Melatonin OR Resveratrol OR 2 - Oxoglutaric acid OR Allantoin OR Apigenin OR Berberine OR Capsaicin OR Chrysin OR Curculigoside OR Curcumin OR Daphnetin OR Diosgenin OR Epigallocatechin Gallate OR Eugenol OR Gallotannin OR Honokiol OR Icariin OR leonurine hydrochloride OR Nicotinamide mononucleotide OR Nobiletin OR Paeoniflorin OR Procyanidin OR Pterostilbene OR Puerarin OR Rutin OR Scutellarin OR Spermidine OR Sphingosine 1-phosphate OR -Ketoglutarate) AND (Diminished ovarian reserve OR Poor ovarian response) AND (IVF OR ICSI OR ART OR Assisted reproductive technology) AND (Randomized controlled trial OR RCT)

Inhibition of these miRNAs reduced tumor growth in vitro and in vivo by recovering MAT1A expression and inducing apoptosis[56]