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We typically recommend a 24 week break after 812 weeks on for chronic protocols the necessity isn't fully established, but it's a sensible conservative approach for long-term use

[DOI] [Google Scholar] 235.Auriema B.E., Correa F.J., Silva R., Soares P.T.S., Lima A.L., Vidal V.A.S., Raices R.S.L., Pollonio M.A.R., Luchese R.H., Esmerino E.A., et al