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Increased HIF-1 activity stimulates ASCT2 transcription alongside other amino acid transporters to boost glutamine uptake which supports cell survival and proliferation within hypoxic tumor settings

Diabetic nephropathy (DN), referring to the deterioration of kidney function associated to both Type 1 and Type 2 diabetes, can progress to chronic kidney disease and, in fact, is a strong predictor of mortality in diabetic patients

The interaction of cardiolipin with amyloid oligomers favors pore formation in the membrane, which causes osmotic swelling, loss of the voltage potential, and release of pro-apoptogenic factors

Inflammatory marker concentrations were recorded pre- and post-treatment as well