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Moreover, they exhibit antioxidant, antibacterial, cholesterol-lowering, and prebiotic properties, and therefore find diverse applications in the cosmetic, pharmaceutical, and medical industries (Saadat et al

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(2016) was based on the use of carbodiimide chemistry to conjugate a poly(N-vinylpyrrolidone) nanoscaffold to insulin: the obtained nanosystems were protected by protease degradation and capable to link to insulin receptors, trigger insulin signaling and promote neuroprotection effects against the dysfunction induced by amyloid-