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This suggests that MK677 may be a useful AD preventative and there is currently research to assess where it may be particularly useful in preventing AD in those who are genetically predisposed to the disease[9]

Administration of radio-labeled proteins, such as insulin-like growth factor-1 (IGF-1) and interferon-beta 1b (IFN-1b), into the rat nose leads to their distribution along trigeminal and olfactory nerve associated pathways and dissemination into both rostral and caudal regions of the rat brain within 3060 min, thus providing evidence of rapid brain access of CNS acting drugs through intranasal delivery [32, 33]