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Excessive TNF expression damages mitochondrial DNA, impairs antioxidant factors, and disrupts mitochondrial complex III activity, leading to increased ROS production

Tranexamic acid is particularly effective on stubborn dark spots caused by sun exposure, hormonal changes, or post-acne hyperpigmentation

If you are prone to hypertrophic or keloid scarring, microneedling may worsen the issue

The underlying molecular mechanisms of melanosome transport can be classified into three categories: membrane transport, cytoskeleton-dependent melanosome transport, and transfer of melanosomes to keratinocytes [223]