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Serious Side Effects and Safety Concerns Rare but Significant Reactions While most cjc1295/ipamorelin side effects remain mild and transient, researchers must monitor for more serious adverse reactions: Allergic Reactions Though rare, some subjects may develop allergic responses ranging from skin rashes to more severe systemic reactions

Studies have shown that those with hypothyroidism have an altered composition of gut bacteria with reduced populations of the beneficial short-chain fatty acid (SCFA)-producing bacteria, and higher levels of inflammation-driving lipopolysaccharides (LPS)-producing bacteria

Persistent, severe, or worsening symptoms should be discussed with a healthcare professional