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This surfactant contains most of surfactant lipids plus the hydrophobic proteins SP-B and SP-C, which are responsible for the spreading of the lipid/protein complexes to form layers at the air-exposed surface of the alveolar epithelium

Through network pharmacology analysis, Guo et al (115) discovered that regulating the AGE-RAGE signaling cascade and the gene expression of its downstream effector molecules is the key mechanism through which bioactive ingredients, such as AS-IV, in Bu Yang Huan Wu Decoction exert anti-PF effects

aeruginosa has many systems dedicated to the regulation of oxidative and heavy metal stress (i.e., a catalase, siderophores, efflux pumps and metal reduction), these systems may compensate for the lack of PmtA in the pmtA mutant, resulting in no defect being observed under the assayed growth conditions

10.1203/00006450-198506000-198506008 Pediatr