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PGP is a stabilising motif derived from biological observation: it resists most endopeptidases and aminopeptidases thanks to rigid prolines (pyrrolidine cycle)

Delivery of therapeutic cells : Cells can be modified via genetic engineering , cell membrane engineering , or selection and preconditioning to increase their extravasation to the region of interest

Proponents argue that the current Biden-era restrictions on compounding of the substances due to safety concerns and a lack of data have fueled a gray market of overseas suppliers, raising safety concerns as Americans inject themselves with unvetted substances

doi: 10.1038/nrm3013