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By contrast, xenoestrogens commonly found in polymers of plastic polycarbonates, such as mineral water bottles and lacquer coating in food cans, can act as endocrine disruptors that significantly alter estrogen-mediated signaling pathways (Brotons et al., 1995

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These results collectively indicate that targeting mitochondrial oxidative stress represents a promising therapeutic approach for mitigating diabetic cardiovascular complications through the preservation of mitochondrial function, attenuation of cellular damage, and reinforcement of cardioprotective mechanisms

Quantification and statistical analysis All grouped data are presented as mean SD or SEM from studies performed at least in triplicate unless otherwise specified