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A inhibits the activity of key mitochondrial enzymes such as electron transport chain enzyme complex IV, pyruvate dehydrogenase (PDH), and -ketoglutarate dehydrogenase (KGDH), reducing the efficiency of electron transfer, diminishing ATP synthesis, and stimulating the production of ROS

Amino acid pattern in human aqueous humor of patients with senile cataract and primary open-angle glaucoma

J Biol Chem 274: 1221312216 BienM,LongenS,WagenerN,ChwallaI,HerrmannJM,RiemerJ (2010) Mitochondrial disulfide bond formation is driven by intersubunit electron transfer in Erv1 and proofread by glutathione

Regular exercise, especially strength training, boosts results