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In order to visualize the GSH-transporter specific cellular uptake, as well as the in vivo pharmacokinetics and biodistribution of GSH conjugated to a hydrophilic agent, GSH is labelled with the hydrophilic fluorescent dye fluorescein isothiocyanate (FITC) or Cy5.5

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Neither approach is appropriate for increased sampling rates and characterization of thousands of individual particles from a single sample

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