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Although probiotics have shown good effects in animal models of OP, the efficacy of probiotics in treating OP may be overestimated, as there are notable differences between animal models and human disease

The following data was recorded on the day of inclusion in the study (initial) and on the third day (final): patient age, diagnosis, sex, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, Sequential Organ Failure Assessment (SOFA) score, ICU length of stay, patient 28-day mortality, and cardiocirculatory parameters

The subject is not even a systematic review of which so many already exist or a meta-analysis

38 Decreased mtDNA copy numbers and increased numbers of mtDNA mutations are observed in various tissues in aging organisms