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Both lipids were first found in the skin of snakes, reptiles and birds, but cholesterol glucoside is now known to occur in human plasma, fibroblasts and gastric mucosa, and in some rat and mouse tissues, where it may act as a mediator of signal transduction in the early stages of heat stress

In addition, a non-enzymatic product of the prostaglandin D2 synthase gene ( PGD2S ), whose expression is upregulated by acetylcarnitine treatment with 100 mg/kg body weight [134], has been shown to have anti-inflammatory properties that may help protect the brain from ischemiareperfusion injury [72]