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What Has Been Learned About How Traumatic Brain Injuries Occur Using the tools described above, researchers have determined that with or without a helmet, when the head contacts a stationary or moving object there is a rapid change in velocity and a possible deformation of the skull

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used in long-term human clinical trials Intravenous injection Used primarily for pharmacokinetic characterization and acute dosing studies in humans Intraperitoneal injection Standard route for chronic rodent studies

If it does not respond to conservative treatments or becomes large and permanent, surgical intervention may be considered