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Description

Detection of protein was by chemiluminescence using ECL substrate (Pierce, Waltham, MA, United States) on a ChemiGenius2 chemi-detection system (Syngene, Frederick, MD, United States)

Human trials have not yet reached Phase 3

Conclusion: Among patients consistent with the current USPI, a composite endpoint of death, liver transplant, and progression to hepatic decompensation and/or PH was less frequent for OCA-treated patients