lippard glutathione cisplatin A cisplatin-based platinum(IV) prodrug containing a s-transferase inhibitor to reverse cisplatin-resistance in non-small cell lung cancer New drug candidate shows promise

V-9302, a competitive small-molecule antagonist of transmembrane glutamine flux, leads to reduced cancer cell growth and proliferation, increased cell death, and increased oxidative stress through the pharmacological blockade of ASCT2, and these activities together promote antitumor responses in vitro and in vivo [180]

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