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Verhage M, Maia AS, Plomp JJ, Brussaard AB, Joost H, Vermeer H, et al

Furthermore, when administered after damage has occurred, it rapidly accelerates the healing of pre-existing ulcers and perforations (Sikiric et al., Dig Dis Sci , 2010)

The reason retatrutide and the approved GLP-1s are titrated up over months is side effects: in the Phase 2 trial, jumping to high doses without titration nearly doubled gastrointestinal side effects for the same weight loss (The Lancet, 2023)