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Shojaie L, Iorga A, Dara L

In combination, the temporary rise in intracellular calcium and the activation of PKC may activate the genes associated with growth hormone synthesis and also stimulate the release of growth hormone molecules out of the pituitary cells

Experimental GPX1 deficiency amplifies certain aspects of aging, namely endothelial dysfunction, vascular remodeling, and invasion of leukocytes in cardiovascular tissue