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Virusdisease 31, 179193

Notably, ROS produced by complex III plays a crucial role in immune activation, which is essential for the activation of various immune cells, including macrophages [69], T cells [70], natural killer (NK) cells [71], and neutrophils [72], as well as the activation of the NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome [73]