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We assessed various microglial profiles, including phagocytic (CD68 + /Iba1 + cells), pro-inflammatory (Cox2 + and iNOS + cells), and pro-regenerative (Arg1 + /Iba1 + cells) microglia, known to follow the dynamics of lesion repair in this model 67,68

Below, we summarize novel therapeutic targets and strategies with clinical application potential to provide more options for disease treatment (Table 1)

Under normal conditions, it helps maintain genomic integrity