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Due to these great properties, tetrasulfide bonds have been utilized in the development of redox-responsive DDSs

Among these, the abnormal aggregation of -synuclein (-syn) to form Lewy bodies, mitochondrial dysfunction, oxidative stress, impaired protein homeostasis, and neuroinflammation (the activation of microglia and astrocytes leads to the release of various inflammatory factors, such as tumor necrosis factor- (TNF-) and interleukin-1 (IL-1), which exacerbate neuronal damage) constitute the key links in the pathophysiology of PD [6, 7]

Supporting nutrients such as vitamin C, amino acids, and antioxidants enhance absorption while promoting hydration, elasticity, and skin repair

For individuals who consume a vegetarian diet, there is not enough vitamin B12 so it is important to supplement