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In reality, the association of telomere length to longevity is modest, and is linked to non-cancer causes of death, and lifestyle choices like smoking, stress, and obesity heavily influence telomere lengthso we dont know if alternative telomere manipulations from a peptide would help at all

Most preclinical trials used weight-adjusted dosing (mg/kg) that doesn't translate directly to fixed human protocols

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At the gene expression level, ZEB1, SIRT1, and CD16 mRNA levels were increased following 5MQ treatment, while TWIST and SERPIN1 mRNA levels were reduced