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Description

Functional Testing That Reveals Mitochondrial Insufficiency Standard laboratory panels do not assess mitochondrial function

Brett Brechner, DO, is our medical director

We thank Shuyun Tian for the assistance in the early stage of the project

These substitutions were capable of altering the specificity of individual substrates for their cognate kinases in predictable ways, an effect that was driven largely, but not completely, by alteration of the K M values (Extended Data Fig