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Taylor A, Bejarano E

When exposed to external factors such as elevated temperatures, chemical toxins, oxidants, and viral pathogens, these erythrocytes undergo significant morphological changes and exhibit apoptotic features

Furthermore, in the same study, expression of poly (GR) 80 in neurons increased ROS levels, inducing oxidative stress and dysregulating redox conditions in C9orf72 iPSCs (Lopez-Gonzalez et al., 2016)