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*Correspondence: Jacinta Serpa, [email protected] This article was submitted to Gastrointestinal Infection, a section of the journal Frontiers in Gastroenterology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Moreover, PL pro SUb2 provides exquisite specificity for K48-linked diubiquitin chains, which makes diubiquitin a suitable substrate compared with monoubiquitin