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The combination is potent because it addresses psoriasis at both the regulatory level, why the immune system is attacking, and the effector level, the specific inflammatory signals doing the damage

PMID: 237 JoshiDCSharmaAPrasadSSinghKKumarMSherawatKet al

The review discusses how physicochemical propertiessuch as size, shape, and surface chemistryinfluence cytotoxicity through mechanisms like oxidative stress, mitochondrial damage, and DNA disruption