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Differential metformin dose-dependent effects on cognition in rats: role of Akt

10.1016/j.freeradbiomed.2011.06.020 Free Radic

final concentration 10 mM) for 30 min (r.t., 600 rpm)

Additionally, certain nanocarriers still face payload limitations- while NLCs improved capacity over solid lipid nanoparticles, some highly bioactive nutraceuticals require even higher loading or multiple compound co-entrapment, pushing existing techniques to their limits (189193)