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(2015) with a total score reduction of 6.5 points and Mischley et al

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The read count (RC) data were processed using the quantile normalization method with EdgeR within R (R: a language and environment for statistical computing

All of these transcriptional effects collectively create a TME optimal for glioma expansion, not only by fueling metabolic needs but also by orchestrating the structural and immunological landscape around the tumor allowing it to thrive ( Figure 4 )