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Arginase inhibition mediates renal tissue protection in diabetic nephropathy by a nitric oxide synthase 3-dependent mechanism

PPT1/2: palmitoyl-protein thioesterase 1/2

Therapeutic potential of the AMPK pathway in modulating aging and cancer Current evidence suggests that AMPK-targeted strategies have shown clearer mechanistic insights in anti-aging research than in oncology, where context-dependent effects and dual roles in tumor progression complicate therapeutic development