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FoB were activated with 5 g/mL anti-IgM (Jackson Immunoresearch 715-006-020), 50 ng/mL CD40 ligand (Bio-techne 8230-CL-050) and 10 ng/mL IL-4 (Miltenyi Biotec 130-097-757)

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Breakthrough advances in targeting microsatellite instability-high CRC have revealed the therapeutic potential of lysosome-mediated immune checkpoint regulation