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If symptoms are severe enough to disrupt daily function, reduce the dose to 2550mg for 57 days, then re-escalate slowly

The Morris water maze, a hippocampal-dependent spatial learning task requiring rats to locate a pedestal hidden beneath the surface of the water by orienting themselves to extra- maze cues was employed to evaluate the impact of the HGF antagonist, Hinge, on the pro- cognitive effects of Dihexa