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Numerous in vitro studies have corroborated the ability of Hcy to induce the release of inflammatory cytokines from ECs, including interleukin-6, interleukin-8, and tumor necrosis factor- (Kamat et al., 2013

In aging research, the compound provides a unique approach to investigating theories of metabolic decline, as NNMT expression increases with age in many tissues, potentially contributing to the NAD+ decline associated with aging processes