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Efficacyand Safety of Sublingual Cyclobenzaprine for the Treatment of Fibromyalgia:Results From a Randomized, Double-Blind, Placebo-Controlled Trial

A more recent Phase I safety trial on healthy volunteers was started in 2015 but puzzlingly, the researchers never published the results , and the trial record was marked completed with no data release

Mechanisms of Action (Preclinical) Angiogenesis: the combination supports new blood vessel formation via VEGF, FGF, and TGF- pathways, enhancing oxygenation and nutrient delivery to stressed tissues in research models