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1 Introduction Fatigue is a common chronic cross-diagnostic symptom ( In CFS, fatigue of unknown origin is a hallmark diagnostic feature ( In hypothyroidism, about 15 20% of patients report fatigue or brain fog even after correction of thyroxine levels to normal with levothyroxine ( L-carnitine supplementation has been suggested to reduce fatigue in both hypothyroidism ( 2 Materials and methods 2.1 Study design and participants The present study is a retrospective analysis of follow-up clinical data