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With that said, taking too much oral, intranasal, or intramuscular B12 may cause some of the following symptoms: Headaches Nausea and vomiting Diarrhea Tingling in the hands and feet Fatigue or weakness You should be aware of medication interactions with B12, such as metformin and proton pump inhibitors (PPIs)

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The authors framed the data as first clear evidence that NNMT inhibitors constitute a viable pharmacological approach to enhance regenerative capacity in aged skeletal muscle

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