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Notably, supplementation with ferrostatin-1 or trolox, both of which are radical-trapping antioxidants and potent inhibitors of ferroptosis, rescued survival but not proliferation under cystine-free conditions (Extended Data Fig

Patients who responded to the drug compared to those who did not, had significant differences in baseline levels as well as in the trajectories of several metabolites, including several gutmicrobiota related metabolites, suggesting that the drug exposure might be impacting gut-microbial ecology differently in the two groups

In particular, we determined lipid profiles in a genetic model of caloric restriction ( eat-2 ), a strain lacking homolog of TGF ( daf-7 ) and in a strain lacking the SREBP /sbp-1 transcription factor

The possibility of a sexual development disorder as a neonatal programming effect is an often raised hypothesis because circulating levels of isoflavones are higher in soy-fed infants compared with cow milk formula or breastfed infants (Reference Andres, Moore and Linam69)