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After the first round screen, 16 compounds stood out as hits and 15 (one compound out of stock) were purchased from TargetMol or CSNPharm

Selenium is a cofactor of many enzymes, and its synthetic selenoproteins (such as glutathione peroxidase and thioredoxin reductase) play an active protective role in Hashimoto disease, thyroiditis, and other diseases [8, 16, 17]