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Inhibit oxLDL-induced endothelial cell injury and restrict atherosclerosis via activating Nrf2 anti-oxidation signal pathway

For instance, higher ATP levels in cancer cells can be associated with stem-like phenotype (multidrug resistance, invasiveness, and spontaneous metastasis

For instance, metformin can activate SIRT1 and regulate related pathways to mitigate LPS-induced SAKI and improve renal function of HFD-/STZ-induced diabetic rats (Xu et al., 2020

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