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This leads to disruption in motor functions, driven by mitochondrial dysfunction, aggregation of alpha-synuclein proteins into Lewy bodies, chronic neuroinflammation, and oxidative stress 33

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doi: 10.1183/13993003.02245-2021 143 BucciarelliVNasiMBiancoFSeferovicJIvkovicVGallinaSet al

In the presence of exogenous GABA, endogenous GABA content increased stably under cold stress, reaching its peak at 49.03 mgkg 1 FW at day 7 a roughly 49-fold increment relative to the untreated control at 0 h