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84 In IBD-related peptides, the most frequent N-terminal amino acids are leucine (L), serine (S), glutamate (E), and glycine (G), while arginine (R) and phenylalanine (F), followed by proline (P) and leucine (L), are predominant at the C-terminus

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In the STEP 1 trial with 1,961 participants, patients taking 2.4 mg semaglutide weekly alongside reduced caloric intake and increased physical activity lost an average of 14.9% of their body weight over 68 weeks

age was calculated for the treatment group, and found to be r = - 0.20 (not significant)