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This perspective has important translational implications, as inhibition of key suppressors may be more effective than direct ferroptosis induction alone, particularly in tumors that have evolved redundant antioxidant defenses

Moffitt, T

Gupta A, Maity A, Ndugire W, Chakraborty S, Ghorpade MS, Hirschbiegel CM, et al

Secondly, the protocol is limited by the number and identity of antibodies included on the array and so may be more useful for detecting glutathionylated proteins under specific experimental conditions where a specific subset of proteins are of interest, rather than when a global screening of the entire proteome is required