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In vitro assays were conducted in parallel with MCF-7 cell cultures to examine the cytotoxic profiles of doxorubicin with and without co-treatment with Frag 176-191

5-Amino-1MQ is a small-molecule compound and selective inhibitor of NNMT (Nicotinamide N-methyltransferase), an enzyme involved in regulating NAD+ metabolism and one-carbon pathway signalling

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This can help control the bleeding in the large intestine to limit blood loss (and the resulting iron deficiency anemia) and reduce inflammation to treat ACD